The 606th meeting of the Sydney University Chemical Society will be held on Monday 21st March in Le Fèvre Lecture Theatre 2 of the Chemistry Building on the campus of The University of Sydney. The speaker will be Prof. M. Reza Ghadiri who will present:

The 2005 Howard Memorial Lectures.

Self-Assembling Peptide Nanotubes: Design and Biological Applications

Prof. M. Reza Ghadiri

The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute

Hollow tubular structures perform diverse biological functions in Nature. In forming such tubular assemblies, biological systems make extensive use of self-assembling and self-organizing strategies. Owing to numerous potential applications in chemistry, biology, and materials science, considerable efforts have recently been devoted to preparation of synthetic nanotubular structures. In this lecture I will highlight various design principles employed in our laboratory for the preparation of synthetic peptide nanotubes. In particular I will discuss the mechanism-based rationale used in the design and discovery of membrane active self-assembling cyclic D, L-a-peptides and their emerging utility as a novel class of antimicrobial agents.

Monday 21st March at 5:30pm

Le Fèvre Lecture Theatre 3

Refreshments from 5:00pm