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Biological and Medicinal Chemistry

The School has extensive expertise in many aspects of Biological, Medicinal and Pharmaceutical Chemistry. These include the design and pharmacology of new drugs, improved formulations for drug delivery, the mechanism of chemical causes for some diseases, the interaction of small molecules and metals with proteins, DNA and other biomaterials, the design and improvement of pesticides and herbicides, and biosensors.

Email enquiries: enquiries@chem.usyd.edu.au

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Researcher Area

Dr Ron Clarke: Biophysical chemistry, Biological membranes and membrane proteins, Regulation and mechanism of charge transport across biological membranes, Voltage-sensitive fluorescent dyes, Na+,K+-ATPase Membrane electrical properties

Prof Max Crossley: Amino acids and peptides of biological importance

Prof Trevor Hambley: Platinum anticancer drugs, Matrix metalloproteinase inhibitors, Sequence selective DNA binding agents, Metal complexes of anti-inflammatory drugs

Prof Kate Jolliffe: Bioorganic chemistry, Synthesis of biologically active cyclic peptides

Dr Meredith Jordan Computational Drug Design

A/Prof Michael Kassiou: Medicinal chemistry and radiochemistry

Prof Brendan Kennedy: Metal complexes of anti-inflammatory drugs

Prof. Cameron Kepert: New materials for drug enantioseparations

Prof Peter Lay: Cr- and Ni-induced cancers, Vanadium bioinorganic chemistry, Structural and spectroscopic studies of heme proteins, Ruthenium and osmium chemistry and anti-cancer drugs, Copper anti-inflammatory drugs

Dr Richard Payne: Medicinal chemistry and chemical biology - Influenza, malaria and tuberculosis drug discovery. Synthesis and evaluation of therapeutic glycopeptides and glycoproteins

Prof Leo Radom: Computational studies of enzyme-catalyzed reactions and peptide radicals

A/Prof Lou Rendina: New agents for Boron Neutron Capture Therapy (BNCT), Interaction of nanomolecular macrocycles with DNA, Metal-DNA chemistry

Dr Peter Rutledge: Biological Chemistry

Dr Mat Todd: Antiparasitic Drug Discovery
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